Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.54 |
| ▸ | GAA | P10253 | 3/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820648 | 0.97 | ALDH1A1 (0.55) | ALDH1A1GAAPKMADORA3KDM4E | |
| SCHEMBL7821246 | 0.92 | RAB9A (0.51) | ALDH1A1GAAPKMADORA3KDM4E | |
| SCHEMBL7817530 | 0.91 | ALDH1A1 (0.52) | ALDH1A1GAAPKMADORA3KDM4E | |
| SCHEMBL7815600 | 0.90 | MAPT (0.55) | ALDH1A1GAAPKMKDM4EHTT | |
| SCHEMBL7815344 | 0.88 | ADORA3 (0.74) | ALDH1A1GAAADORA3KDM4ESMN1; SMN2 | |
| SCHEMBL7820629 | 0.87 | MAPT (0.61) | ALDH1A1GAAPKMADORA3KDM4E | |
| SCHEMBL7817200 | 0.87 | TSHR (0.69) | ALDH1A1GAAPKMADORA3KDM4E | |
| SCHEMBL7818193 | 0.85 | BACE1 (0.62) | ALDH1A1PKMADORA3RAB9ASMN1; SMN2 | |
| SCHEMBL7814462 | 0.85 | ALDH1A1 (0.55) | ALDH1A1GAAPKMADORA3KDM4E | |
| SCHEMBL13334005 | 0.81 | PTGS2 (0.45) | ALDH1A1GAAPKMHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6265127-B1 | 1, 4-dihydrophyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1109070-A2 | 1,4-Dihydropyridine charge control agents for electrostatographic toners and developers | EASTMAN KODAK COMPANY (US) | 2001-06-20 | — | — | EP | disclosed |