Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 6/20 | 0.68 |
| ▸ | CYP11B1 | P15538 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 4/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NR2E3 | Q9Y5X4 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.38 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HK1 | P19367 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3852371 | 0.83 | CYP11B2 (0.47) | CYP11B2MAOAKMT2APPARGNPSR1 | |
| SCHEMBL1606034 | 0.81 | CYP11B2 (1.00) | CYP11B2CYP11B1MAOATBXAS1CYP2A6 | |
| SCHEMBL7803219 | 0.81 | CYP11B2 (0.64) | CYP11B2CYP11B1MAOATBXAS1CYP2A6 | |
| SCHEMBL7815564 | 0.81 | CYP11B2 (0.64) | CYP11B2CYP11B1MAOATBXAS1PPARG | |
| SCHEMBL7803234 | 0.78 | CYP11B2 (0.60) | CYP11B2CYP11B1MAOATBXAS1KMT2A | |
| SCHEMBL7811673 | 0.77 | CYP11B2 (0.58) | CYP11B2CYP11B1MAOATBXAS1PPARG | |
| SCHEMBL7812395 | 0.77 | CYP11B2 (0.58) | CYP11B2CYP11B1MAOATBXAS1KDM4E | |
| SCHEMBL7817257 | 0.75 | CYP11B2 (0.53) | CYP11B2CYP11B1MAOATBXAS1PPARG | |
| SCHEMBL15332857 | 0.74 | CYP11B2 (0.46) | CYP11B2CYP11B1TBXAS1RXFP1KMT2A | |
| SCHEMBL10175606 | 0.74 | CYP11B2 (0.60) | CYP11B2CYP11B1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |