Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 5/20 | 0.64 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.48 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 2/20 | 0.39 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.39 |
| ▸ | TACR1 | P25103 | 1/20 | 0.39 |
| ▸ | VHL | P40337 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.37 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811673 | 0.88 | CYP11B2 (0.58) | CYP11B2MKNK1MKNK2TBXAS1CYP11B1 | |
| SCHEMBL7803234 | 0.87 | CYP11B2 (0.60) | CYP11B2MKNK1MKNK2TBXAS1CYP11B1 | |
| SCHEMBL7803263 | 0.81 | CYP11B2 (0.53) | CYP11B2TBXAS1CYP11B1MAOATACR1 | |
| SCHEMBL7817257 | 0.81 | CYP11B2 (0.53) | CYP11B2TBXAS1CYP11B1MAOATACR1 | |
| SCHEMBL7815329 | 0.81 | CYP11B2 (0.68) | CYP11B2TBXAS1CYP11B1MAOAPPARG | |
| SCHEMBL7803153 | 0.80 | CYP11B2 (0.51) | CYP11B2MKNK1MKNK2TBXAS1CYP11B1 | |
| SCHEMBL1606034 | 0.78 | CYP11B2 (1.00) | CYP11B2TBXAS1CYP11B1MAOACYP2A6 | |
| SCHEMBL7803219 | 0.78 | CYP11B2 (0.64) | CYP11B2TBXAS1CYP11B1MAOACYP2A6 | |
| SCHEMBL7812395 | 0.76 | CYP11B2 (0.58) | CYP11B2TBXAS1CYP11B1MAOAABCG2 | |
| SCHEMBL7803167 | 0.72 | CYP11B2 (0.50) | CYP11B2TBXAS1CYP11B1MAOATACR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |