Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.43 |
| ▸ | CDK1 | P06493 | 1/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | ATM | Q13315 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19052340 | 0.83 | MEN1 (0.50) | CYP11B2ALDH1A1LMNAGRIK2HSD17B10 | |
| SCHEMBL7815329 | 0.83 | CYP11B2 (0.68) | CYP11B2HSD17B10CYP2C19KMT2AKDM4E | |
| SCHEMBL22005104 | 0.81 | KDM4E (0.50) | CYP11B2ALDH1A1LMNAGRIK2HSD17B10 | |
| SCHEMBL28811227 | 0.80 | CYP11B2 (0.56) | CYP11B2ALDH1A1LMNAGRIK2HSD17B10 | |
| SCHEMBL10067380 | 0.79 | CYP11B2 (0.68) | CYP11B2ALDH1A1LMNAHSD17B10CYP2C19 | |
| SCHEMBL28282805 | 0.79 | CCNB2 (0.43) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL3856618 | 0.78 | PPARG (0.51) | CCNB2CDK1CCNB1GSK3BCCNB3 | |
| SCHEMBL3855156 | 0.78 | GRIK2 (0.50) | ALDH1A1LMNAGRIK2CYP2C19MEN1 | |
| SCHEMBL3854575 | 0.78 | ALDH1A1 (0.49) | ALDH1A1LMNAHSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL3856953 | 0.77 | ESR1 (0.52) | CYP11B2ALDH1A1LMNAGRIK2HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7582773-B2 | Substituted phenyl indoles | WYETH (US) | 2009-09-01 | — | — | US | disclosed |
| US-20050070592-A1 | Substituted phenyl indoles | WYETH (US) | 2005-03-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050070592-A1 | Substituted phenyl indoles | TPH2, IDO2, AANAT | CYP11B2 141/4885CCNB2 1115/4885CDK1 1265/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.