Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | USP2 | O75604 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9395434 | 0.82 | TSHR (0.48) | TDP1TSHRALOX15SMN1; SMN2CYP3A4 | |
| SCHEMBL9395446 | 0.82 | TSHR (0.48) | TDP1TSHRALOX15SMN1; SMN2CYP3A4 | |
| SCHEMBL28263077 | 0.81 | TSHR (0.51) | TDP1TSHRSMN1; SMN2CYP3A4MAPT | |
| SCHEMBL13670835 | 0.79 | ALOX15 (0.40) | TSHRALOX15SMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL5716962 | 0.78 | SMN1; SMN2 (0.44) | TSHRALOX15SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL5716961 | 0.78 | SMN1; SMN2 (0.44) | TSHRALOX15SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL1906626 | 0.78 | ALDH1A1 (0.50) | TSHRALOX15SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL1906628 | 0.78 | ALDH1A1 (0.50) | TSHRALOX15SMN1; SMN2CYP3A4MAPT | |
| SCHEMBL11015965 | 0.77 | TSHR (0.43) | TDP1TSHRSMN1; SMN2CYP3A4MAPT | |
| SCHEMBL11015960 | 0.77 | TSHR (0.43) | TDP1TSHRSMN1; SMN2CYP3A4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010053858-A1 | Processes for producing epsilon caprolactones and/or hydrates and/or esters thereof | TJADEN ERIK BRUCE (US) | 2001-12-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010053858-A1 | Processes for producing epsilon caprolactones and/or hydrates and/or esters thereof | CHRNE, POLL, ECH1 | TDP1 1298/4885TSHR 2609/4885ALOX15 2408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.