Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.51 |
| ▸ | TBXAS1 | P24557 | 5/20 | 0.46 |
| ▸ | TACR1 | P25103 | 2/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 2/20 | 0.35 |
| ▸ | MKNK2 | Q9HBH9 | 2/20 | 0.35 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811673 | 0.80 | CYP11B2 (0.58) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL7803165 | 0.80 | CYP11B2 (0.48) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL7803263 | 0.80 | CYP11B2 (0.53) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL7815564 | 0.80 | CYP11B2 (0.64) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL7817257 | 0.78 | CYP11B2 (0.53) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL7808262 | 0.77 | CYP11B2 (0.52) | CYP11B2TBXAS1CYP11B1MAOA | |
| SCHEMBL7803182 | 0.77 | CYP11B2 (0.49) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL7803234 | 0.77 | CYP11B2 (0.60) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL7803145 | 0.75 | TBXAS1 (0.55) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL7811601 | 0.75 | TBXAS1 (0.55) | CYP11B2TBXAS1CYP11B1PTGES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |