Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B2 | P19099 | 4/20 | 0.53 |
| ▸ | TBXAS1 | P24557 | 6/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | MAOA | P21397 | 1/20 | 0.39 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811673 | 0.82 | CYP11B2 (0.58) | CYP11B2TBXAS1TACR1ALDH1A1CYP11B1 | |
| SCHEMBL7815564 | 0.81 | CYP11B2 (0.64) | CYP11B2TBXAS1NR4A2TACR1CYP11B1 | |
| SCHEMBL7803234 | 0.81 | CYP11B2 (0.60) | CYP11B2TBXAS1HDAC1NR4A2TACR1 | |
| SCHEMBL7803153 | 0.80 | CYP11B2 (0.51) | CYP11B2TBXAS1HDAC1NR4A2TACR1 | |
| SCHEMBL7812395 | 0.80 | CYP11B2 (0.58) | CYP11B2TBXAS1NR4A2KDM4EALDH1A1 | |
| SCHEMBL7817257 | 0.80 | CYP11B2 (0.53) | CYP11B2TBXAS1HDAC1NR4A2TACR1 | |
| SCHEMBL7803167 | 0.79 | CYP11B2 (0.50) | CYP11B2TBXAS1NR4A2TACR1GABRA1 | |
| SCHEMBL7796987 | 0.79 | TBXAS1 (0.71) | CYP11B2TBXAS1TACR1CYP11B1MAOA | |
| SCHEMBL11033906 | 0.75 | TBXAS1 (0.75) | TBXAS1 | |
| SCHEMBL12646562 | 0.75 | HDAC1 (0.60) | CYP11B2TBXAS1HDAC1KDM4ENPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0949259-B1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | NIKKEN CHEMICALS CO LTD (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-6184238-B1 | ANTIALLERGENS, ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-02-06 | — | — | US | disclosed |
| EP-0949259-A1 | N-HYDROXYUREA DERIVATIVES AND MEDICINAL COMPOSITIONS CONTAINING THE SAME | Nikken Chemicals Company, Limited (JP) | 1999-10-13 | — | — | EP | disclosed |