Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | CES2 | O00748 | 2/20 | 0.33 |
| ▸ | CES1 | P23141 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.32 |
| ▸ | MAPT | P10636 | 5/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.32 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.32 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.32 |
| ▸ | GMNN | O75496 | 1/20 | 0.32 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.32 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.32 |
| ▸ | GSR | P00390 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27734128 | 0.81 | CES2 (0.35) | KMT2APOLBCES2CES1ALDH1A1 | |
| SCHEMBL8345590 | 0.76 | ALDH1A1 (0.44) | KMT2ALMNACES2CES1ALDH1A1 | |
| SCHEMBL27671644 | 0.75 | ACHE (0.40) | KMT2ALMNAALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL7459017 | 0.75 | ALDH1A1 (0.31) | ALDH1A1GSR | |
| SCHEMBL27502523 | 0.71 | CES2 (0.38) | KMT2APOLBCES2CES1ALDH1A1 | |
| SCHEMBL9001399 | 0.68 | CES1 (0.34) | KMT2ACES2CES1ALDH1A1MAPT | |
| SCHEMBL28019025 | 0.68 | MAPT (0.34) | KMT2ALMNACES2CES1ALDH1A1 | |
| SCHEMBL27335677 | 0.67 | CES1 (0.33) | KMT2ACES2CES1ALDH1A1MAPT | |
| SCHEMBL9149341 | 0.65 | SMN1; SMN2 (0.35) | KMT2ALMNACES2CES1ALDH1A1 | |
| SCHEMBL27597829 | 0.65 | ALDH1A1 (0.35) | KMT2ALMNAALDH1A1MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1150962-A1 | PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2001-11-07 | — | — | EP | disclosed |
| WO-2000049003-A1 | PROCESS FOR THE PREPARATION OF 6-(PERFLUOROALKYL)URACIL COMPOUNDS FROM CARBAMATE COMPOUNDS | AMERICAN CYANAMID COMPANY (US) | 2000-08-24 | — | — | WO | disclosed |