Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7818154 | 0.94 | ALDH1A1 (0.47) | MARS1 | |
| SCHEMBL7821468 | 0.82 | MARS1 (0.60) | MARS1 | |
| SCHEMBL7818445 | 0.72 | KDM4E (0.46) | MARS1 | |
| SCHEMBL7978429 | 0.71 | HDAC1 (0.55) | — | |
| SCHEMBL5668076 | 0.70 | MARS1 (0.59) | MARS1 | |
| Hydrochloric Acid SCHEMBL5669755 | 0.69 | MARS1 (0.58) | MARS1 | |
| SCHEMBL10070268 | 0.69 | CTSV (0.58) | MARS1 | |
| Ammonia Solution, Strong SCHEMBL5667906 | 0.69 | MARS1 (0.58) | MARS1 | |
| SCHEMBL7818007 | 0.69 | MARS1 (0.48) | MARS1 | |
| SCHEMBL11147008 | 0.68 | CNR1 (0.60) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6320051-B1 | AMINO(NH) OR OXYGEN(O) SUBSTITUTED, ENZYME INHIBITORS OF STAPHLOCCOCUS AUREUS METHIONYL T-RNA SYNTHETASE (MRS); ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-20 | — | — | US | claimed |
| EP-1084110-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 2001-03-21 | — | — | EP | claimed |
| WO-1999055677-A1 | QUINOLONES USED AS MRS INHIBITORS AND BACTERICIDES | SMITHKLINE BEECHAM PLC (GB) | 1999-11-04 | — | — | WO | claimed |
| US-6320051-B1 | AMINO(NH) OR OXYGEN(O) SUBSTITUTED, ENZYME INHIBITORS OF STAPHLOCCOCUS AUREUS METHIONYL T-RNA SYNTHETASE (MRS); ANTIBACTERIAL AGENTS | SMITHKLINE BEECHAM PLC (GB) | 2001-11-20 | — | — | US | disclosed |