Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | WDR5 | P61964 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SI | P14410 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | PGR | P06401 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | CRHBP | P24387 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6440266 | 0.89 | LMNA (0.52) | MYCWDR5MGAMGAASI | |
| SCHEMBL6797025 | 0.83 | TSHR (0.53) | MGAMGAASIPKMMGAM2 | |
| SCHEMBL6436943 | 0.83 | KCNH2 (0.62) | KCNH2ADORA1PRKACAPRKACGPRKACB | |
| SCHEMBL6776150 | 0.79 | LMNA (0.50) | MYCWDR5MGAMGAASI | |
| SCHEMBL5077502 | 0.74 | ALDH1A1 (0.43) | MYCWDR5MGAMGAASI | |
| Dinitrophenylene SCHEMBL27864502 | 0.73 | TSHR (0.57) | GAALMNATSHRALDH1A1MAPT | |
| SCHEMBL689735 | 0.73 | VCAM1 (0.66) | GAALMNATSHRALDH1A1MAPT | |
| SCHEMBL6771411 | 0.72 | KCNH2 (0.62) | KCNH2ALDH1A1MAPTADORA1 | |
| Nitrogen SCHEMBL28796067 | 0.71 | VCAM1 (0.64) | GAALMNATSHRALDH1A1MAPT | |
| SCHEMBL7276378 | 0.70 | LMNA (0.52) | GAALMNATSHRALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1123274-A1 | SUBSTITUTED PHENYL DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 2001-08-16 | — | — | EP | disclosed |
| WO-2000024707-A1 | SUBSTITUTED PHENYL DERIVATIVES, THEIR PREPARATION AND USE | NEUROSEARCH A/S (DK) | 2000-05-04 | — | — | WO | disclosed |