Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | PABPC1 | P11940 | 2/20 | 0.44 |
| ▸ | EIF4H | Q15056 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.43 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.43 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824213 | 0.80 | RAB9A (0.41) | SMN1; SMN2HTTNPC1L3MBTL1RAB9A | |
| SCHEMBL8799382 | 0.79 | TYK2 (0.37) | SMN1; SMN2RAB9AALDH1A1KMT2APDE4B | |
| SCHEMBL8341754 | 0.79 | TP53 (0.48) | SMN1; SMN2HTTRXFP1NPC1RAB9A | |
| SCHEMBL7827083 | 0.78 | TYK2 (0.47) | SMN1; SMN2HPGDHTTKDM4EL3MBTL1 | |
| SCHEMBL7827508 | 0.77 | GPR35 (0.50) | SMN1; SMN2HPGDHTTRXFP1KDM4E | |
| SCHEMBL7816537 | 0.76 | GPR35 (0.41) | SMN1; SMN2HPGDNPC1RAB9AALDH1A1 | |
| SCHEMBL8345039 | 0.75 | PDE4D (0.41) | SMN1; SMN2HTTNPC1KDM4ERAB9A | |
| SCHEMBL7825378 | 0.74 | GAA (0.42) | ALDH1A1GAAPOLBKMT2AMEN1 | |
| SCHEMBL7831836 | 0.74 | MAPT (0.53) | SMN1; SMN2HPGDHTTRXFP1NPC1 | |
| SCHEMBL8345841 | 0.73 | GPR35 (0.39) | SMN1; SMN2HPGDKDM4EALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-B1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-06-20 | — | — | EP | disclosed |
| US-5858995-A | ADMINISTERING TO HUMANS AND ANIMALS IN THE TREATMENT OF DISEASES CAUSED BY ABNORMAL BONE METABOLISM | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-01-12 | — | — | US | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |