Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYK2 | P29597 | 2/20 | 0.37 |
| ▸ | JAK2 | O60674 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | JAK1 | P23458 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.35 |
| ▸ | GHSR | Q92847 | 3/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824213 | 0.91 | RAB9A (0.41) | TYK2JAK2CYP3A4JAK1RAB9A | |
| SCHEMBL7827083 | 0.86 | TYK2 (0.47) | TYK2RAB9AALDH1A1LMNAMAPT | |
| SCHEMBL7816537 | 0.84 | GPR35 (0.41) | TYK2JAK2JAK1RAB9AALDH1A1 | |
| SCHEMBL7825378 | 0.82 | GAA (0.42) | CYP3A4ALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL8345841 | 0.81 | GPR35 (0.39) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL8345039 | 0.81 | PDE4D (0.41) | RAB9AALDH1A1LMNAMAPTNPSR1 | |
| SCHEMBL7825606 | 0.80 | GPR35 (0.43) | TYK2JAK2CYP3A4JAK1RAB9A | |
| SCHEMBL7817437 | 0.79 | ALDH1A1 (0.39) | ALDH1A1LMNAMAPTNPSR1KMT2A | |
| SCHEMBL8799546 | 0.79 | ALDH1A1 (0.39) | RAB9AALDH1A1TP53LMNAMAPT | |
| SCHEMBL7822840 | 0.79 | POLB (0.44) | TYK2JAK2JAK1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0757682-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-02-12 | — | — | EP | disclosed |
| WO-1995029907-A1 | BENZOFURAN DERIVATIVES USEFUL AS INHIBITORS OF BONE RESORPTION | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1995-11-09 | — | — | WO | disclosed |