Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 11/20 | 0.37 |
| ▸ | RARB | P10826 | 10/20 | 0.37 |
| ▸ | RARG | P13631 | 9/20 | 0.32 |
| ▸ | RARA | P10276 | 7/20 | 0.32 |
| ▸ | RXRB | P28702 | 2/20 | 0.32 |
| ▸ | RXRG | P48443 | 2/20 | 0.32 |
| ▸ | NR4A2 | P43354 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | CYP26A1 | O43174 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
| ▸ | USP2 | O75604 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7816745 | 1.00 | RXRA (0.37) | RXRARARBRARGRARARXRB | |
| SCHEMBL7805839 | 0.83 | RARB (0.32) | RXRARARB | |
| SCHEMBL7810811 | 0.81 | CYP26A1 (0.43) | RXRARARBRARGRARARXRB | |
| SCHEMBL7812405 | 0.81 | CYP26A1 (0.43) | RXRARARBRARGRARARXRB | |
| SCHEMBL7816750 | 0.78 | RXRA (0.33) | RXRARARBRARGRARARXRB | |
| SCHEMBL7812219 | 0.77 | RXRA (0.43) | RXRARARBRARGRARARXRB | |
| SCHEMBL7812403 | 0.76 | RXRA (0.35) | RXRARARBRARGRARARXRB | |
| SCHEMBL8425328 | 0.73 | — | — | |
| SCHEMBL7813043 | 0.73 | RARA (0.34) | RXRARARBRARGRARARXRG | |
| SCHEMBL7806225 | 0.73 | RARA (0.34) | RXRARARBRARGRARARXRG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0816352-B1 | Bi-aryl heterocyclic compounds and their use in human or veterinary medicine and in cosmetics | CT INTERNAT DE (FR) | 2001-02-21 | — | — | EP | claimed |