Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608772 | 0.85 | ALDH1A1 (0.41) | — | |
| SCHEMBL11678711 | 0.84 | KMT2A (0.47) | NOTUMKDM4EKMT2A | |
| Oxalic Acid SCHEMBL7832615 | 0.83 | ALDH1A1 (0.45) | KDM4EKMT2A | |
| SCHEMBL11678636 | 0.82 | HRH3 (0.41) | — | |
| SCHEMBL7829391 | 0.80 | SLC6A1 (0.46) | NOTUMNR1I3KDM4EKMT2A | |
| SCHEMBL11680936 | 0.78 | CHRM2 (0.40) | — | |
| SCHEMBL11678169 | 0.77 | SLC6A1 (0.42) | — | |
| SCHEMBL11679331 | 0.77 | SLC22A1 (0.41) | — | |
| SCHEMBL11680271 | 0.77 | NOTUM (0.43) | NOTUMKMT2A | |
| SCHEMBL11677581 | 0.76 | SIGMAR1 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6214816-B1 | ANTIDIABETIC AGENTS, ANALGESICS AND ANTIINFLAMMATORY AGENTS | NOVO NORDISK A/S (DK) | 2001-04-10 | — | — | US | disclosed |
| EP-1071679-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999047517-A1 | NOVEL HETEROCYCLIC COMPOUNDS | NOVO NORDISK A/S (DK) | 1999-09-23 | — | — | WO | disclosed |