Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MPO | P05164 | 16/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 8/20 | 0.45 |
| ▸ | HTR1A | P08908 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825966 | 0.97 | MPO (0.42) | MPOSLC6A4HTR1A | |
| SCHEMBL7817689 | 0.90 | HTR2C (0.39) | SLC6A4HTR1A | |
| SCHEMBL7828217 | 0.88 | HTR1A (0.39) | SLC6A4HTR1A | |
| SCHEMBL7817703 | 0.88 | HTR2A (0.43) | MPOSLC6A4HTR1A | |
| SCHEMBL7824434 | 0.85 | HTR2A (0.44) | MPOSLC6A4HTR1A | |
| SCHEMBL7817710 | 0.85 | HTR1A (0.36) | SLC6A4HTR1A | |
| SCHEMBL7817353 | 0.84 | SLC6A4 (0.46) | SLC6A4HTR1A | |
| SCHEMBL7827683 | 0.80 | LMNA (0.30) | — | |
| SCHEMBL1322750 | 0.80 | SLC6A4 (0.33) | SLC6A4 | |
| SCHEMBL8692253 | 0.73 | MPO (0.31) | MPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | claimed |
| EP-0861248-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-09-02 | — | — | EP | claimed |
| WO-1997017343-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-05-15 | — | — | WO | claimed |
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | disclosed |