Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.42 |
| ▸ | HTR2B | P41595 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.39 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PGR | P06401 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7811977 | 0.90 | ATM (0.41) | ATML3MBTL1CA12CA9POLB | |
| SCHEMBL7825809 | 0.90 | FFAR1 (0.44) | ATML3MBTL1NPC1RAB9AMAPT | |
| SCHEMBL7821131 | 0.88 | PGR (0.48) | ATML3MBTL1POLBLMNAHTT | |
| SCHEMBL7821557 | 0.87 | SERPINE1 (0.40) | ATML3MBTL1POLBNPC1RAB9A | |
| SCHEMBL7820690 | 0.87 | ATM (0.39) | ATML3MBTL1POLBKCNA5MEN1 | |
| SCHEMBL9195467 | 0.86 | TSHR (0.40) | POLBNPC1RAB9ATSHRMEN1 | |
| SCHEMBL7821015 | 0.86 | PGR (0.44) | ATML3MBTL1POLBLMNASMN1; SMN2 | |
| SCHEMBL7824308 | 0.85 | KCNA5 (0.39) | ATML3MBTL1POLBKCNA5MEN1 | |
| SCHEMBL7822282 | 0.85 | ESR1 (0.48) | POLBLMNASMN1; SMN2RAB9ATSHR | |
| SCHEMBL3442031 | 0.81 | ABCC9 (0.48) | POLBSMN1; SMN2KCNA5MAPTKCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |