Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KCNE1 | P15382 | 3/20 | 0.41 |
| ▸ | KCNQ1 | P51787 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.37 |
| ▸ | EPAS1 | Q99814 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.36 |
| ▸ | RORC | P51449 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819583 | 0.90 | ATM (0.52) | ATML3MBTL1KCNE1KCNQ1NPC1 | |
| SCHEMBL7821557 | 0.88 | SERPINE1 (0.40) | ATML3MBTL1NPC1RAB9A | |
| SCHEMBL7821131 | 0.87 | PGR (0.48) | ATML3MBTL1MAPT | |
| SCHEMBL7811977 | 0.87 | ATM (0.41) | ATML3MBTL1KCNE1KCNQ1NPC1 | |
| SCHEMBL9195467 | 0.83 | TSHR (0.40) | KCNE1KCNQ1NPC1RAB9AMAPT | |
| SCHEMBL7820690 | 0.82 | ATM (0.39) | ATML3MBTL1KCNE1KCNQ1HPGD | |
| SCHEMBL7821015 | 0.81 | PGR (0.44) | ATML3MBTL1MAPT | |
| SCHEMBL7846865 | 0.78 | ABCC9 (0.49) | TDP1NPC1RAB9AMAPTNPSR1 | |
| SCHEMBL3442782 | 0.77 | ABCC9 (0.52) | KCNE1KCNQ1 | |
| SCHEMBL482379 | 0.77 | ABCC9 (0.52) | KCNE1KCNQ1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |