Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ALPL | P05186 | 1/20 | 0.46 |
| ▸ | ALPI | P09923 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819583 | 0.85 | ATM (0.52) | KMT2ATSHRMAPTLMNASMN1; SMN2 | |
| SCHEMBL7846865 | 0.85 | ABCC9 (0.49) | KMT2ATSHRMAPK1MAPTLMNA | |
| SCHEMBL7824308 | 0.82 | KCNA5 (0.39) | KMT2AMEN1POLB | |
| SCHEMBL9195467 | 0.81 | TSHR (0.40) | KMT2ATSHRMAPTALDH1A1MEN1 | |
| SCHEMBL482008 | 0.78 | ABCC9 (0.48) | MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL3442031 | 0.78 | ABCC9 (0.48) | MAPTALDH1A1SMN1; SMN2POLB | |
| SCHEMBL7821527 | 0.78 | ESR1 (0.46) | ESR1KMT2ATSHRMAPK1HSD17B10 | |
| SCHEMBL9198079 | 0.77 | IDO1 (0.38) | — | |
| SCHEMBL7821581 | 0.77 | ABCB1 (0.36) | KMT2AMEN1POLB | |
| SCHEMBL7825809 | 0.76 | FFAR1 (0.44) | HSD17B10MAPTHPGDNPSR1HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828733-B1 | BENZOPYRANS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | NOVARTIS AG (CH) | 2001-09-05 | — | — | EP | disclosed |