Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 2/20 | 0.33 |
| ▸ | CCR9 | P51686 | 5/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.31 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8546620 | 0.91 | MEN1 (0.32) | GPR84 | |
| SCHEMBL7817749 | 0.72 | LMNA (0.37) | PTGS2PTGS1 | |
| SCHEMBL7825262 | 0.72 | KMT2A (0.39) | CCR9 | |
| SCHEMBL7818383 | 0.72 | LMNA (0.37) | PTGS2PTGS1 | |
| SCHEMBL7830253 | 0.69 | MEN1 (0.52) | — | |
| SCHEMBL7806728 | 0.69 | CDC25B (0.56) | ADORA2APTGS2PTGS1 | |
| SCHEMBL29780065 | 0.66 | GPR84 (0.40) | GPR84 | |
| SCHEMBL6674009 | 0.65 | CSNK2A2 (0.44) | ADORA2A | |
| SCHEMBL8540388 | 0.65 | ECE1 (0.45) | CCR9PTGS2 | |
| SCHEMBL308115 | 0.64 | ADORA2A (0.76) | ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0750619-B1 | HETERO-ANNULATED INDAZOLES | NOVUSPHARMA SPA (IT) | 2001-05-30 | — | — | EP | disclosed |
| US-5596097-A | ANTITUMOR AGENTS | THE UNIVERSITY OF VERMONT (US) | 1997-01-21 | — | — | US | disclosed |
| EP-0750619-A1 | HETERO-ANNULATED INDAZOLES | BOEHRINGER MANNHEIM ITALIA S.p.A. (IT) | 1997-01-02 | — | — | EP | disclosed |
| WO-1995024407-A1 | HETERO-ANNULATED INDAZOLES | BOEHRINGER MANNHEIM ITALIA, S.P.A. (IT) | 1995-09-14 | — | — | WO | disclosed |