Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | MAPT | P10636 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10928551 | 0.81 | MAPT (0.46) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL29060004 | 0.79 | LTA4H (0.53) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL28452624 | 0.78 | ALDH1A1 (0.54) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL6734762 | 0.76 | GSK3A (0.60) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL1619449 | 0.76 | ALDH1A1 (0.68) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL6805065 | 0.75 | ALDH1A1 (0.48) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL8447095 | 0.75 | L3MBTL1 (0.54) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL17525778 | 0.75 | HRH3 (0.47) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL6944202 | 0.74 | HTT (0.64) | ALDH1A1MEN1MAPTKMT2AHSD17B10 | |
| SCHEMBL8114202 | 0.74 | HTT (0.64) | ALDH1A1MEN1MAPTKMT2AHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087977-A1 | THIENODIPYRIDINE DERIVATIVES, PRODUCTION AND USE THEREOF | Takeda Chemical Industries, Ltd. (JP) | 2001-04-04 | — | — | EP | disclosed |
| WO-1999065916-A1 | THIENODIPYRIDINE DERIVATIVES, PRODUCTION AND USE THEREOF | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-12-23 | — | — | WO | disclosed |