SCHEMBL29060004

SCHEMBL29060004

O=C1CCC(=O)N1Cc1ccc(-c2cccs2)s1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 1/20 0.53
DPP4 P27487 4/20 0.51
ALDH1A1 P00352 5/20 0.41
MAPT P10636 2/20 0.41
MEN1 O00255 2/20 0.41
KMT2A Q03164 2/20 0.41
HSD17B10 Q99714 2/20 0.41
GAA P10253 3/20 0.41
KDM4E B2RXH2 3/20 0.40
LMNA P02545 2/20 0.40
L3MBTL1 Q9Y468 2/20 0.40
GLA P06280 1/20 0.40
NPC1 O15118 3/20 0.39
RAB9A P51151 3/20 0.39
TP53 P04637 1/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
NFKB1 P19838 1/20 0.39
MAPK1 P28482 1/20 0.39
CASP1 P29466 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7820085 0.79 ALDH1A1 (0.61) ALDH1A1MAPTMEN1KMT2AHSD17B10
SCHEMBL8575790 0.73 LTA4H (0.67) LTA4HDPP4ALDH1A1MAPTMEN1
SCHEMBL21823759 0.73 LTA4H (0.71) LTA4HDPP4ALDH1A1MAPTMEN1
SCHEMBL21386863 0.72 DPP4 (0.68) LTA4HDPP4ALDH1A1MAPTMEN1
SCHEMBL2031590 0.72 DPP4 (0.68) LTA4HDPP4ALDH1A1MAPTMEN1
SCHEMBL32667653 0.72 ALDH1A1 (0.55) LTA4HDPP4ALDH1A1MEN1KMT2A
SCHEMBL13857522 0.71 DPP4 (0.53) LTA4HDPP4ALDH1A1MAPTMEN1
SCHEMBL2690127 0.70 LTA4H (1.00) LTA4HDPP4ALDH1A1MAPTMEN1
SCHEMBL799550 0.70 LTA4H (0.67) LTA4HDPP4ALDH1A1MAPTMEN1
SCHEMBL406832 0.70 DPP4 (0.96) LTA4HDPP4ALDH1A1MAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116669811-A Compositions and methods for enhancing visual function 加利福尼亚大学董事会 2023-08-29 CN disclosed