Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | CASP6 | P55212 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 3/20 | 0.50 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820370 | 0.88 | PLAU (0.52) | LMNAKDM4EPOLBCASP6PLAU | |
| SCHEMBL7820537 | 0.78 | ALDH1A1 (0.48) | LMNAKDM4EKMT2AMEN1ACHE | |
| SCHEMBL28056008 | 0.75 | NPC1 (0.72) | POLBNPC1RAB9AKMT2AADORA3 | |
| SCHEMBL8900732 | 0.75 | PLAU (0.57) | LMNAKDM4EPOLBCASP6PLAU | |
| SCHEMBL10465204 | 0.74 | MGAM (0.56) | LMNAKDM4EPOLBCASP6PLAU | |
| SCHEMBL16114562 | 0.72 | RAB9A (0.49) | LMNAKDM4EPOLBPLAUNPC1 | |
| SCHEMBL21070179 | 0.71 | ROCK2 (0.58) | NPC1RAB9AKMT2ASMN1; SMN2NFKB1 | |
| SCHEMBL15651778 | 0.70 | PLAU (0.50) | LMNAKDM4EPOLBCASP6PLAU | |
| SCHEMBL7820237 | 0.70 | NPC1 (0.44) | LMNAKDM4EPOLBNPC1RAB9A | |
| SCHEMBL15450991 | 0.70 | DYRK1A (0.51) | LMNAKDM4ENPC1RAB9AKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0533200-B1 | Preparation and use of novel activated carbamates | WATERS INVESTMENTS LTD (US) | 2001-12-05 | — | — | EP | claimed |