Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.76 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.73 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.73 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.73 |
| ▸ | GAA | P10253 | 2/20 | 0.73 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.73 |
| ▸ | GFER | P55789 | 1/20 | 0.59 |
| ▸ | PNLIP | P16233 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | SMO | Q99835 | 1/20 | 0.58 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.56 |
| ▸ | PRSS12 | P56730 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13927135 | 0.91 | ALDH1A1 (0.92) | ALDH1A1CYP1A2CYP3A4ALOX12GFER | |
| SCHEMBL45299 | 0.87 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4ALOX12GFER | |
| SCHEMBL1991348 | 0.87 | ALDH1A1 (1.00) | ALDH1A1CYP1A2CYP3A4ALOX12GFER | |
| SCHEMBL7825446 | 0.84 | GAA (1.00) | ALDH1A1CYP1A2CYP3A4ALOX12GAA | |
| SCHEMBL7822055 | 0.84 | FADS1 (0.69) | ALDH1A1CYP1A2CYP3A4ALOX12GAA | |
| SCHEMBL12189649 | 0.84 | ALDH1A1 (0.85) | ALDH1A1CYP1A2CYP3A4ALOX12GAA | |
| SCHEMBL29360103 | 0.84 | ALDH1A1 (0.79) | ALDH1A1CYP1A2CYP3A4ALOX12GFER | |
| SCHEMBL2117583 | 0.84 | SMO (0.75) | CYP1A2CYP2C19PNLIPSMOMAPT | |
| SCHEMBL1336628 | 0.84 | ALDH1A1 (0.79) | ALDH1A1CYP1A2CYP3A4ALOX12GFER | |
| SCHEMBL2058694 | 0.84 | ALDH1A1 (0.79) | ALDH1A1CYP1A2CYP3A4ALOX12GFER |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011026107-A1 | PHTHALANILATE COMPOUNDS AND METHODS OF USE | UNIVERSITY OF NOTRE DAME DU LAC (US) | 2011-03-03 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |
| US-4857305-A | N-phenylphthalisoimides as ultraviolet radiation absorbers | STEPAN COMPANY (US) | 1989-08-15 | — | — | US | disclosed |
| US-4788054-A | SUNSCREEN AGENTS FOR PLASTICS, SKINS, FIBERS, COATINGS | STEPAN COMPANY (US) | 1988-11-29 | — | — | US | disclosed |