Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | KIF11 | P52732 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | RXRB | P28702 | 5/20 | 0.40 |
| ▸ | RXRA | P19793 | 4/20 | 0.40 |
| ▸ | RXRG | P48443 | 4/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31294407 | 0.78 | ALDH1A1 (0.46) | ALOX15TSHRHSD17B10KIF11KDM4E | |
| SCHEMBL23024812 | 0.76 | NPC1 (0.41) | KIF11TRPV1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL7835864 | 0.74 | CYP2C19 (0.46) | KIF11TDP1ALDH1A1RXRBRXRA | |
| SCHEMBL18408971 | 0.74 | NPC1 (0.42) | KIF11ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL10627376 | 0.73 | TRPV1 (0.47) | ALOX15TSHRHSD17B10KIF11TDP1 | |
| SCHEMBL14817232 | 0.72 | TRPV1 (0.36) | KIF11ALDH1A1TRPV1CYP2C19NPC1 | |
| SCHEMBL13952384 | 0.72 | ALOX15 (0.44) | ALOX15TSHRHSD17B10KIF11KDM4E | |
| SCHEMBL8834371 | 0.72 | ALOX15 (0.62) | ALOX15TSHRHSD17B10KDM4EALDH1A1 | |
| SCHEMBL18610641 | 0.71 | CNR2 (0.40) | KIF11ALDH1A1TRPV1NPC1RAB9A | |
| SCHEMBL6535262 | 0.71 | ESR1 (0.55) | TDP1CYP2C19HIF1ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |