SCHEMBL14817232

SCHEMBL14817232

CC(C)(CC=O)c1ccc2c(c1)CCC2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 2/20 0.36
ALDH1A1 P00352 3/20 0.36
KIF11 P52732 2/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA7 P43166 1/20 0.35
CA14 Q9ULX7 1/20 0.35
NPC1 O15118 5/20 0.34
RAB9A P51151 5/20 0.34
SMN1; SMN2 Q16637 3/20 0.34
NFKB1 P19838 2/20 0.34
NFKB2 Q00653 2/20 0.34
RELA Q04206 2/20 0.34
MAPT P10636 1/20 0.34
CYP1A2 P05177 1/20 0.33
CYP3A4 P08684 1/20 0.33
CYP2D6 P10635 1/20 0.33
HPGD P15428 1/20 0.33
CYP2C19 P33261 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18408971 0.79 NPC1 (0.42) ALDH1A1KIF11CA12CA1CA2
SCHEMBL14817234 0.77 TRPV1 (0.36) TRPV1ALDH1A1KIF11CA12CA1
SCHEMBL18610641 0.76 CNR2 (0.40) TRPV1ALDH1A1KIF11CA12CA1
SCHEMBL5691582 0.75 KIF11 (0.36) TRPV1ALDH1A1KIF11NPC1RAB9A
SCHEMBL4579825 0.74 ALDH1A1 (0.42) TRPV1ALDH1A1KIF11CA12CA1
SCHEMBL1726817 0.74 TRPV1 (0.43) TRPV1ALDH1A1KIF11CA12CA1
SCHEMBL23024812 0.74 NPC1 (0.41) TRPV1KIF11NPC1RAB9ASMN1; SMN2
SCHEMBL18410997 0.73 CNR2 (0.43)
SCHEMBL7820680 0.72 ALOX15 (0.46) TRPV1ALDH1A1KIF11NPC1RAB9A
SCHEMBL27473294 0.72 CNR2 (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3218457-B1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS GIVAUDAN SA (CH) 2019-01-02 EP disclosed
US-9441184-B2 Floral perfuming compositions as substitutes for LILIAL® FIRMENICH SA (CH) 2016-09-13 US disclosed
US-20140234244-A1 FLORAL PERFUMING COMPOSITIONS AS SUBSTITUTES FOR LILIAL® FIRMENICH SA (CH) 2014-08-21 US disclosed
EP-2760983-A1 FLORAL PERFUMING COMPOSITIONS AS SUBSTITUTES FOR LILIAL Firmenich SA (CH) 2014-08-06 EP disclosed
CN-103874755-A Floral perfuming composition for use as LILILIAL substitute FIRMENICH & CIE 2014-06-18 CN disclosed
WO-2013045301-A1 FLORAL PERFUMING COMPOSITIONS AS SUBSTITUTES FOR LILIAL® FIRMENICH SA (CH) 2013-04-04 WO disclosed