Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.55 |
| ▸ | RORC | P51449 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.52 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.52 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.52 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820959 | 0.90 | TP53 (0.56) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL6900995 | 0.85 | CYP1A2 (0.63) | POLBMEN1KMT2AMAPTLMNA | |
| SCHEMBL12189440 | 0.80 | MAPT (0.58) | POLBKDM4EMEN1KMT2AMAPT | |
| SCHEMBL16737157 | 0.80 | MEN1 (0.69) | POLBKDM4EMEN1KMT2AMAPT | |
| Naptalam SCHEMBL54940 | 0.78 | HSD17B10 (0.74) | POLBKDM4EMEN1KMT2AMAPT | |
| Naptalam SCHEMBL8537412 | 0.78 | HSD17B10 (0.74) | POLBKDM4EMEN1KMT2AMAPT | |
| Naptalam SCHEMBL29469565 | 0.78 | HSD17B10 (0.74) | POLBKDM4EMEN1KMT2AMAPT | |
| Naptalam SCHEMBL29610802 | 0.78 | HSD17B10 (0.74) | POLBKDM4EMEN1KMT2AMAPT | |
| Naptalam SCHEMBL984498 | 0.77 | HSD17B10 (0.72) | POLBKDM4EMEN1KMT2AMAPT | |
| SCHEMBL7825604 | 0.76 | KCNMA1 (0.73) | KDM4EMEN1KMT2AMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |