Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.73 |
| ▸ | MEN1 | O00255 | 6/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.59 |
| ▸ | PHGDH | O43175 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | NPC1 | O15118 | 3/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | GAA | P10253 | 2/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | DDX3X | O00571 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ATM | Q13315 | 1/20 | 0.56 |
| ▸ | GFER | P55789 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL394289 | 0.89 | KCNMA1 (0.79) | KCNMA1MEN1KMT2APHGDHALDH1A1 | |
| SCHEMBL7722700 | 0.88 | ALDH1A1 (0.68) | KCNMA1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7717663 | 0.86 | ALDH1A1 (0.66) | KCNMA1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL7759260 | 0.84 | KCNMA1 (1.00) | KCNMA1MEN1KMT2APHGDHALDH1A1 | |
| SCHEMBL11492887 | 0.83 | KCNMA1 (0.71) | KCNMA1MEN1KMT2APHGDHALDH1A1 | |
| SCHEMBL5181163 | 0.83 | KMT2A (0.76) | KCNMA1MEN1KMT2APHGDHALDH1A1 | |
| SCHEMBL7159815 | 0.82 | CRHBP (0.68) | KCNMA1MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL641989 | 0.82 | PHGDH (0.77) | KCNMA1MEN1KMT2APHGDHALDH1A1 | |
| SCHEMBL10521271 | 0.82 | KCNMA1 (0.69) | KCNMA1MEN1KMT2APHGDHALDH1A1 | |
| SCHEMBL25054248 | 0.81 | KMT2A (0.69) | KCNMA1MEN1KMT2AGAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150328329-A1 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | American University of Cairo (EG) | 2015-11-19 | — | — | US | disclosed |
| WO-2014081856-A2 | LIGANDS THAT TARGET HCV-E2 BINDING SITES ON CD81 AND THERAPEUTIC METHODS USING THEM | AZZAZY HASSAN (EG) | 2014-05-30 | — | — | WO | disclosed |
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |