Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.42 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.31 |
| ▸ | GABRR2 | P28476 | 2/20 | 0.31 |
| ▸ | BLM | P54132 | 2/20 | 0.31 |
| ▸ | GABRR3 | A8MPY1 | 1/20 | 0.31 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL453090 | 1.00 | TSHR (0.42) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL7812907 | 0.87 | TSHR (0.36) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL5704732 | 0.87 | TSHR (0.36) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL899318 | 0.80 | TSHR (0.44) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL899316 | 0.80 | TSHR (0.44) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL9187017 | 0.78 | TSHR (0.42) | TSHRTP53EGLN1EGLN3LMNA | |
| SCHEMBL17186622 | 0.77 | — | — | |
| SCHEMBL408424 | 0.77 | — | — | |
| SCHEMBL239930 | 0.77 | — | — | |
| SCHEMBL15754827 | 0.76 | TSHR (0.40) | TSHRTP53EGLN1EGLN3LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |