Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 18/20 | 0.61 |
| ▸ | PDK2 | Q15119 | 18/20 | 0.61 |
| ▸ | PDK3 | Q15120 | 18/20 | 0.61 |
| ▸ | PDK4 | Q16654 | 18/20 | 0.61 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.53 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7832297 | 0.86 | PDK1 (0.60) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL7833541 | 0.81 | LCK (0.68) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL7832380 | 0.81 | ABCC9 (0.67) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL7832614 | 0.78 | PDK1 (0.59) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL7829630 | 0.78 | PDK1 (0.59) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL6348877 | 0.77 | PDK1 (1.00) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL5735974 | 0.77 | PDK1 (1.00) | PDK1PDK2PDK3PDK4 | |
| SCHEMBL27529530 | 0.76 | PDK1 (0.63) | PDK1PDK2PDK3PDK4NR1H2 | |
| SCHEMBL27553215 | 0.74 | PDK1 (0.70) | PDK1PDK2PDK3PDK4NR1H2 | |
| SCHEMBL27553216 | 0.74 | PDK1 (0.70) | PDK1PDK2PDK3PDK4NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798288-B1 | TRICICLIC COMPOUNDS | KYOWA HAKKO KOGYO KK (JP) | 2001-05-16 | — | — | EP | disclosed |
| US-5726325-A | FOR TREATING URINARY INCONTINENCE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1998-03-10 | — | — | US | disclosed |
| EP-0798288-A1 | TRICICLIC COMPOUNDS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-10-01 | — | — | EP | disclosed |