Ammonia Solution, Strong

Ammonia Solution, Strong

SCHEMBL782137

Cc1ccccc1C(C)(C)O.N

nearest known ligand 0.46

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
CASR P41180 1/20 0.43
TSHR P16473 2/20 0.43
ACHE P22303 2/20 0.43
ALDH1A1 P00352 4/20 0.41
TDP1 Q9NUW8 2/20 0.41
CYP3A4 P08684 2/20 0.38
CYP2C19 P33261 1/20 0.38
CA2 P00918 2/20 0.37
TRPA1 O75762 1/20 0.37
ATM Q13315 1/20 0.37
CHRM3 P20309 2/20 0.37
PDK1 Q15118 1/20 0.35
PDK2 Q15119 1/20 0.35
PDK3 Q15120 1/20 0.35
PDK4 Q16654 1/20 0.35
HSD11B1 P28845 1/20 0.35
CA1 P00915 1/20 0.35
CA7 P43166 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30471342 0.97 GABRA1 (0.48) GABRA1GABRB2CASRTSHRACHE
SCHEMBL796229 0.97 GABRA1 (0.48) GABRA1GABRB2CASRTSHRACHE
SCHEMBL15976427 0.87 GABRA1 (0.48) GABRA1GABRB2CASRTSHRACHE
Bicarbonate SCHEMBL16179256 0.85 GABRA1 (0.39) GABRA1GABRB2CASRTSHRACHE
SCHEMBL874172 0.82 CASR (0.53) GABRA1GABRB2CASRTSHRACHE
Ammonia Solution, Strong SCHEMBL27927923 0.81 TRPA1 (0.50) GABRA1GABRB2CASRTSHRACHE
SCHEMBL2059781 0.81 ALDH1A1 (0.50) GABRA1GABRB2CASRTSHRALDH1A1
SCHEMBL29506834 0.81 ALDH1A1 (0.50) GABRA1GABRB2CASRTSHRALDH1A1
SCHEMBL10094721 0.79 GABRA1 (0.42) GABRA1GABRB2CASRTSHRACHE
SCHEMBL8785533 0.79 TSHR (0.47) GABRA1GABRB2CASRTSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102361902-A Prepreg and molded body produced therefrom at low temperature EVONIK DEGUSSA GMBH 2012-02-22 CN claimed
CN-110062794-A Hard coating with high chemical and mechanical resistance 科思创德国股份有限公司 2019-07-26 CN disclosed
CN-109890865-A Production of plastics by catalytic crosslinking of blocked polyisocyanates 科思创德国股份有限公司 2019-06-14 CN disclosed
CN-109843961-A The method and equipment for coating of coil and stsip of blocked polyisocyanate containing catalytic crosslinking 科思创德国股份有限公司 2019-06-04 CN disclosed
CN-108329464-A polycarbonate resin, its manufacturing method and optical molded body 三菱瓦斯化学株式会社 2018-07-27 CN disclosed
CN-104769007-B Polycarbonate resin, process for producing the same, and optical molded article 三菱瓦斯化学株式会社 2018-04-06 CN disclosed
CN-107501942-A It can be molded organic siliconresin, composition and its semiconductor light-emitting elements of shaping 北京康美特科技股份有限公司 2017-12-22 CN disclosed
EP-1654331-B1 PAINT COMPRISING A LIQUID PHASE AND AN ACTIVE POWDER PHASE AKZO NOBEL COATINGS INT BV (NL) 2013-12-11 EP disclosed
US-20120070571-A1 PAINT COMPRISING A LIQUID PHASE AND AN ACTIVE POWDER PHASE AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2012-03-22 US disclosed
US-8048482-B2 Paint comprising a liquid phase and an active powder phase AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2011-11-01 US disclosed
US-20060222765-A1 Paint comprising a liquid phase and an active powder phase AKZO NOBEL COATING INTERNATIONAL B.V. (NL) 2006-10-05 US disclosed
EP-1654331-A1 PAINT COMPRISING A LIQUID PHASE AND AN ACTIVE POWDER PHASE Akzo Nobel Coatings International B.V. (NL) 2006-05-10 EP disclosed
WO-2005017054-A1 PAINT COMPRISING A LIQUID PHASE AND AN ACTIVE POWDER PHASE AKZO NOBEL COATINGS INTERNATIONAL B.V. (NL) 2005-02-24 WO disclosed
EP-0399508-B1 Organic electroluminescent device MITSUBISHI CHEM IND (JP) 1994-02-02 EP disclosed
US-5104749-A Hydrazone compound for hole injection transfer layer; stability, low driving voltage MITSUBISHI KASEI CORPORATION (JP) 1992-04-14 US disclosed
EP-0399508-A1 Organic electroluminescent device MITSUBISHI KASEI CORPORATION (JP) 1990-11-28 EP disclosed