SCHEMBL874172

SCHEMBL874172

Cc1ccccc1C(C)(O)c1ccccc1C

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CASR P41180 5/20 0.53
GABRA1 P14867 1/20 0.48
GABRB2 P47870 1/20 0.48
TSHR P16473 2/20 0.45
ACHE P22303 2/20 0.45
ALDH1A1 P00352 3/20 0.42
TDP1 Q9NUW8 2/20 0.42
CA2 P00918 2/20 0.42
CA1 P00915 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
TRPA1 O75762 1/20 0.39
ATM Q13315 1/20 0.39
CHRM3 P20309 2/20 0.38
PDK1 Q15118 1/20 0.36
PDK2 Q15119 1/20 0.36
PDK3 Q15120 1/20 0.36
PDK4 Q16654 1/20 0.36
CYP3A4 P08684 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19130511 0.86 CASR (0.47) CASRGABRA1GABRB2TSHRACHE
SCHEMBL3848041 0.86 CASR (0.47) CASRGABRA1GABRB2TSHRACHE
SCHEMBL30471342 0.84 GABRA1 (0.48) CASRGABRA1GABRB2TSHRACHE
SCHEMBL15976427 0.84 GABRA1 (0.48) CASRGABRA1GABRB2TSHRACHE
SCHEMBL796229 0.84 GABRA1 (0.48) CASRGABRA1GABRB2TSHRACHE
SCHEMBL11336791 0.83 CASR (0.45) CASRGABRA1GABRB2TSHRACHE
Ammonia Solution, Strong SCHEMBL782137 0.82 GABRA1 (0.46) CASRGABRA1GABRB2TSHRACHE
SCHEMBL8785533 0.81 TSHR (0.47) CASRGABRA1GABRB2TSHRACHE
SCHEMBL10437577 0.81 ACHE (0.47) CASRGABRA1GABRB2TSHRACHE
SCHEMBL31589377 0.81 TSHR (0.47) CASRGABRA1GABRB2TSHRACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240115652-A1 TISSUE OCCLUDING AGENT COMPRISING AN IEIKIEIKIEIKI PEPTIDE 3 D MATRIX LTD (JP) 2024-04-11 US claimed
US-11801281-B2 Tissue occluding agent comprising an ieikieikieiki peptide 3-D MATRIX, LTD. (JP) 2023-10-31 US claimed
EP-4183425-A1 TISSUE PLUG 3-D Matrix Ltd. (JP) 2023-05-24 EP claimed
US-20220193184-A1 TISSUE OCCLUDING AGENT COMPRISING AN IEIKIEIKIEIKI PEPTIDE 3-D MATRIX, LTD. (JP) 2022-06-23 US claimed
EP-3800197-A1 TISSUE PLUG 3-D Matrix Ltd. (JP) 2021-04-07 EP claimed
EP-3470093-B1 TISSUE PLUG 3 D MATRIX LTD (JP) 2020-08-19 EP claimed
US-20200222496-A1 TISSUE OCCLUDING AGENT 3-D MATRIX, LTD. (JP) 2020-07-16 US claimed
US-10596225-B2 Tissue occluding agent comprising an IEIKIEIKIEIKI peptide 3-D MATRIX, LTD. (JP) 2020-03-24 US claimed
US-10576123-B2 Tissue occluding agent comprising an IEIKIEIKIEIKI peptide 3-D MATRIX, LTD. (JP) 2020-03-03 US claimed
EP-3470093-A1 TISSUE PLUG 3-D Matrix Ltd. (JP) 2019-04-17 EP claimed
EP-3238749-B1 TISSUE PLUG 3 D MATRIX LTD (JP) 2018-09-19 EP claimed
EP-3238749-A1 TISSUE PLUG 3-D Matrix Ltd. (JP) 2017-11-01 EP claimed
US-20150105336-A1 MUCOSA-ELEVATING AGENT 3-D MATRIX, LTD. (JP) 2015-04-16 US claimed
EP-2823830-A1 MUCOSA-ELEVATING AGENT 3-D Matrix, Ltd. (JP) 2015-01-14 EP claimed
US-20140038909-A1 TISSUE OCCLUDING AGENT 3-D MATRIX, LTD. (JP) 2014-02-06 US claimed
US-20110201541-A1 TISSUE OCCLUDING AGENT 3-D MATRIX, LTD. (JP) 2011-08-18 US claimed
EP-2345433-A1 TISSUE PLUG 3-D Matrix, Ltd. (JP) 2011-07-20 EP claimed
US-20240115652-A1 TISSUE OCCLUDING AGENT COMPRISING AN IEIKIEIKIEIKI PEPTIDE 3 D MATRIX LTD (JP) 2024-04-11 US disclosed
JP-2006160698-A VEGF PRODUCTION PROMOTER, HAIR GROWER AND WOUND HEALING AGENT NOEVIR CO LTD 2006-06-22 JP disclosed
EP-1561476-A1 DEODORANT COMPOSITION Takasago International Corporation (JP) 2005-08-10 EP disclosed