Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | ALPG | P10696 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APEX1 | P27695 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA6 | P23280 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2057249 | 0.83 | CA12 (0.52) | SMN1; SMN2KMT2AMEN1ALDH1A1CA12 | |
| Alpha-Cyano-3-Hydroxycinnamic Acid SCHEMBL7821767 | 0.75 | KDM4E (0.68) | LMNAHPGDKMT2AMEN1ALDH1A1 | |
| SCHEMBL6744132 | 0.74 | L3MBTL1 (0.42) | HPGDSMN1; SMN2KMT2APOLBL3MBTL1 | |
| SCHEMBL15190627 | 0.73 | CA12 (0.39) | LMNASMN1; SMN2ALDH1A1CA12CA1 | |
| SCHEMBL23465352 | 0.72 | SMN1; SMN2 (0.45) | LMNAHPGDSMN1; SMN2ALPGKMT2A | |
| SCHEMBL8743711 | 0.72 | SMN1; SMN2 (0.45) | LMNAHPGDSMN1; SMN2ALPGKMT2A | |
| SCHEMBL196920 | 0.69 | LMNA (0.62) | LMNAHPGDSMN1; SMN2ALPGALDH1A1 | |
| SCHEMBL4632807 | 0.69 | LMNA (0.62) | LMNAHPGDSMN1; SMN2ALPGALDH1A1 | |
| SCHEMBL196919 | 0.69 | LMNA (0.62) | LMNAHPGDSMN1; SMN2ALPGALDH1A1 | |
| SCHEMBL305984 | 0.68 | ALDH1A1 (0.46) | LMNAHPGDSMN1; SMN2KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |