Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 2/20 | 0.45 |
| ▸ | F9 | P00740 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | CBFB | Q13951 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.42 |
| ▸ | HPGD | P15428 | 6/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.41 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.40 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8143148 | 0.99 | TNIK (0.44) | TNIKF9KMT2ACBFBALDH1A1 | |
| SCHEMBL7822232 | 0.93 | TNIK (0.45) | TNIKF9KMT2AALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8143145 | 0.92 | TNIK (0.44) | TNIKF9KMT2AALDH1A1HPGD | |
| SCHEMBL7832392 | 0.85 | CBFB (0.47) | TNIKF9KMT2ACBFBALDH1A1 | |
| SCHEMBL7821991 | 0.83 | NPC1 (0.55) | F9KMT2ACBFBALDH1A1HPGD | |
| SCHEMBL7834577 | 0.82 | CYP11B1 (0.51) | F9KMT2ACBFBALDH1A1HPGD | |
| Hydrochloric Acid SCHEMBL8155594 | 0.82 | NPC1 (0.54) | F9KMT2ACBFBALDH1A1HPGD | |
| SCHEMBL7833700 | 0.81 | CBFB (0.43) | F9CBFBALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL7832389 | 0.77 | ENPP2 (0.47) | TNIKF9KMT2ACBFBALDH1A1 | |
| SCHEMBL7822350 | 0.77 | ALDH1A1 (0.50) | F9KMT2ACBFBALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |