Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCC9 | O60706 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.38 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9195467 | 0.86 | TSHR (0.40) | ABCC9ALDH1A1TSHRMAPTMEN1 | |
| SCHEMBL7822282 | 0.85 | ESR1 (0.48) | SMN1; SMN2ALDH1A1TSHRMAPTMAPK1 | |
| SCHEMBL9198079 | 0.81 | IDO1 (0.38) | ABCC9 | |
| SCHEMBL7819583 | 0.81 | ATM (0.52) | SMN1; SMN2TSHRHTTMAPTLMNA | |
| SCHEMBL7836596 | 0.79 | ABCC9 (0.56) | ABCC9SMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL7836593 | 0.79 | ABCC9 (0.56) | ABCC9SMN1; SMN2ALDH1A1TSHRHTT | |
| SCHEMBL482008 | 0.78 | ABCC9 (0.48) | ABCC9SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL3442031 | 0.78 | ABCC9 (0.48) | ABCC9SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7811977 | 0.78 | ATM (0.41) | ABCC9MAPTNPC1RAB9A | |
| SCHEMBL7825809 | 0.78 | FFAR1 (0.44) | MAPTNPSR1TDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0747374-B1 | Sulfonamido substituted benzopyran potassium channel activators | BRISTOL MYERS SQUIBB CO (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0747374-A1 | Sulfonamido substituted benzopyran potassium channel activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |