Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | PORCN | Q9H237 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | F9 | P00740 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | PARP3 | Q9Y6F1 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | WNT3A | P56704 | 1/20 | 0.43 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.43 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.43 |
| ▸ | ACP1 | P24666 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7822350 | 0.92 | ALDH1A1 (0.50) | ALDH1A1PORCNMEN1POLBKMT2A | |
| SCHEMBL7822768 | 0.82 | IDH1 (0.48) | ALDH1A1PORCNMEN1KMT2ACYP3A4 | |
| SCHEMBL7836354 | 0.80 | CYP4Z1 (0.55) | ALDH1A1POLBKMT2AF9SMN1; SMN2 | |
| SCHEMBL7835277 | 0.80 | F9 (0.41) | PORCNMEN1KMT2ACYP3A4CYP2D6 | |
| Hydrochloric Acid SCHEMBL8148418 | 0.79 | CYP4Z1 (0.54) | ALDH1A1POLBKMT2AF9SMN1; SMN2 | |
| SCHEMBL4071088 | 0.77 | HSD17B10 (0.56) | ALDH1A1MEN1KMT2ACYP3A4CYP2D6 | |
| SCHEMBL7407358 | 0.77 | CBFB (0.50) | POLBF9RAB9ALMNACYP19A1 | |
| SCHEMBL7822232 | 0.77 | TNIK (0.45) | ALDH1A1PORCNMEN1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL8155236 | 0.77 | F9 (0.46) | TDP1F9LMNACYP19A1CYP11B1 | |
| SCHEMBL15685943 | 0.76 | ALDH1A1 (0.74) | ALDH1A1MEN1POLBKMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0894795-B1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-06-06 | — | — | EP | disclosed |
| EP-0894795-A1 | Benzimidazole, benzoxazole and benzothiazole derivatives, their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1999-02-03 | — | — | EP | disclosed |