Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | MAP2K4 | P45985 | 2/20 | 0.46 |
| ▸ | MAPK6 | Q16659 | 2/20 | 0.46 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.46 |
| ▸ | MAPKAPK5 | Q8IW41 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | DHODH | Q02127 | 3/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.45 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.44 |
| ▸ | RXRB | P28702 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | RXRG | P48443 | 1/20 | 0.44 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7824222 | 0.84 | KMO (0.50) | MAPTRXRARXRBKDM4EALDH1A1 | |
| SCHEMBL400608 | 0.76 | NTRK1 (0.52) | DHODHCYP2C8RXRARXRBKDM4E | |
| SCHEMBL3975183 | 0.76 | MAP4K4 (0.58) | MAPTTP53POLBSLC6A2P2RY14 | |
| SCHEMBL30445247 | 0.75 | CYP2C8 (0.50) | MAPK1MAP2K4MAPK6MAPKAPK3DHODH | |
| SCHEMBL6491306 | 0.74 | PTPN1 (0.46) | DHODHRXRARXRBMAP4K4 | |
| SCHEMBL25148616 | 0.73 | SLC6A2 (0.43) | MAPTTP53POLBDHODHSLC6A2 | |
| SCHEMBL3745471 | 0.72 | KEAP1 (0.54) | MAPK1MAP2K4MAPK6MAPKAPK3MAPKAPK5 | |
| SCHEMBL28059821 | 0.71 | KDM4E (0.49) | DHODHSLC6A2P2RY14CYP2C8RXRA | |
| SCHEMBL330660 | 0.71 | ACMSD (0.66) | SLC6A2P2RY14RXRARXRBKDM4E | |
| SCHEMBL4197626 | 0.71 | TDP1 (0.61) | MAPTDHODHKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |