Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 3/20 | 0.53 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | RARB | P10826 | 6/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL264975 | 0.89 | FFAR1 (0.65) | FFAR1KEAP1ALDH1A1HSD17B10RARB | |
| Acetonitrile SCHEMBL28166106 | 0.82 | FFAR1 (0.53) | FFAR1KEAP1ALDH1A1HSD17B10RARB | |
| SCHEMBL7822999 | 0.80 | ALDH1A1 (0.41) | FFAR1KEAP1NR1H4ALDH1A1EPHX2 | |
| SCHEMBL69746 | 0.78 | FFAR1 (0.81) | FFAR1KEAP1L3MBTL1LMNA | |
| Phenyl Propionic Acid SCHEMBL5786016 | 0.77 | KEAP1 (0.79) | FFAR1KEAP1ALDH1A1MAPT | |
| SCHEMBL6786019 | 0.77 | HSD17B10 (0.79) | FFAR1KEAP1NR1H4EPHX2HSD17B10 | |
| SCHEMBL1058497 | 0.77 | ALDH1A1 (0.67) | ALDH1A1HSD17B10RARBL3MBTL1SRD5A2 | |
| SCHEMBL803658 | 0.77 | HSD17B10 (0.72) | FFAR1NR1H4ALDH1A1HSD17B10RARB | |
| SCHEMBL659834 | 0.76 | PLK1 (0.68) | FFAR1KEAP1NR1H4ALDH1A1EPHX2 | |
| Hydrochloric Acid SCHEMBL25264643 | 0.76 | FFAR1 (0.77) | FFAR1KEAP1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |