Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.45 |
| ▸ | CA9 | Q16790 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7820667 | 0.89 | CA12 (0.53) | POLBALDH1A1KMT2ATDP1KDM4E | |
| SCHEMBL25179009 | 0.81 | GAA (0.58) | POLBALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL7104681 | 0.81 | ALDH1A1 (0.53) | POLBALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL7109979 | 0.81 | POLB (0.65) | POLBALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL7822933 | 0.77 | L3MBTL1 (0.71) | POLBALDH1A1KMT2AMEN1CYP2C19 | |
| SCHEMBL5150800 | 0.76 | HDAC1 (0.74) | ALDH1A1KMT2ATDP1KDM4EMEN1 | |
| SCHEMBL7291409 | 0.76 | ALDH1A1 (0.54) | POLBALDH1A1KMT2AKDM4EMEN1 | |
| SCHEMBL7814839 | 0.76 | MEN1 (0.68) | POLBALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL7719057 | 0.76 | POLB (0.71) | POLBALDH1A1GAAKMT2ATDP1 | |
| SCHEMBL7827099 | 0.75 | KMT2A (0.64) | POLBALDH1A1KMT2ATDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |