Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.47 |
| ▸ | CA9 | Q16790 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7819674 | 0.87 | KDM4E (0.44) | CA12CA9CA2KDM4EALDH1A1 | |
| SCHEMBL8580296 | 0.85 | MAOB (0.49) | CA12CA9CA2KDM4EHSD17B10 | |
| SCHEMBL9255027 | 0.84 | CA12 (0.45) | CA12CA9CA2KDM4EHSD17B10 | |
| SCHEMBL7201722 | 0.83 | KDM4E (0.42) | CA12CA9CA2KDM4EALDH1A1 | |
| SCHEMBL7203116 | 0.81 | SMN1; SMN2 (0.43) | CA12CA9CA2KDM4EHSD17B10 | |
| SCHEMBL30606875 | 0.80 | MTNR1A (0.46) | CA12CA9CA2KDM4EHSD17B10 | |
| SCHEMBL7818300 | 0.73 | KDM4E (0.47) | CA12CA9CA2KDM4EHSD17B10 | |
| SCHEMBL28731104 | 0.72 | — | — | |
| SCHEMBL7823486 | 0.72 | ALDH1A1 (0.49) | KDM4EHSD17B10ALDH1A1HPGDTP53 | |
| SCHEMBL8579581 | 0.72 | KDM4E (0.48) | CA12CA9CA2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439909-A | 2-Substituted with amide or thioamide group; antioxidant for lipoproteins, antilipemic agents, anticholesterol agents | ADIR ET COMPAGNIE (FR) | 1995-08-08 | — | — | US | disclosed |
| US-5420132-A | Antilipemic agents | ADIR ET COMPAGNIE (FR) | 1995-05-30 | — | — | US | disclosed |