Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 6/20 | 0.41 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.39 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | RORB | Q92753 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.37 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.37 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7823689 | 0.83 | PPARG (0.47) | PPARGPPARACASP1TLR8TLR7 | |
| SCHEMBL7823683 | 0.83 | PPARG (0.47) | PPARGPPARACASP1TLR8TLR7 | |
| SCHEMBL4008948 | 0.72 | PPARG (0.67) | PPARGPPARATLR8TLR7TP53 | |
| SCHEMBL4008943 | 0.70 | PPARG (0.52) | PPARGPPARATLR8TLR7KDM4E | |
| SCHEMBL23519064 | 0.69 | PPARG (0.51) | PPARGPPARAKDM4EMEN1ALDH1A1 | |
| SCHEMBL16829591 | 0.65 | CASP1 (0.49) | CASP1MEN1MAPTKMT2ASMN1; SMN2 | |
| SCHEMBL11570463 | 0.63 | KDM4E (0.50) | PPARGPPARAKDM4EALDH1A1MAPT | |
| SCHEMBL3685278 | 0.63 | CASP1 (0.56) | CASP1ALDH1A1HTTKMT2A | |
| SCHEMBL31506886 | 0.63 | CASP1 (0.56) | CASP1ALDH1A1HTTKMT2A | |
| SCHEMBL22939 | 0.63 | CASP1 (0.56) | CASP1ALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |