Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.64 |
| ▸ | HTT | P42858 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | GLA | P06280 | 1/20 | 0.53 |
| ▸ | GRK2 | P25098 | 1/20 | 0.52 |
| ▸ | CASP6 | P55212 | 1/20 | 0.52 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.52 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031444 | 0.84 | MEN1 (0.56) | HTTRAB9APOLBKMT2ASMN1; SMN2 | |
| SCHEMBL28799461 | 0.82 | LMNA (0.58) | HTTRAB9APOLBKMT2ASMN1; SMN2 | |
| SCHEMBL25877653 | 0.82 | LMNA (0.60) | HTTRAB9APOLBKMT2ASMN1; SMN2 | |
| SCHEMBL11311560 | 0.78 | AR (0.62) | HTTRAB9ASMN1; SMN2LMNAALDH1A1 | |
| SCHEMBL2853073 | 0.77 | LMNA (0.73) | HTTRAB9APOLBKMT2ASMN1; SMN2 | |
| SCHEMBL2853072 | 0.77 | LMNA (0.73) | HTTRAB9APOLBKMT2ASMN1; SMN2 | |
| SCHEMBL19420106 | 0.76 | HTT (0.72) | L3MBTL1HTTRAB9APOLBKMT2A | |
| SCHEMBL7814995 | 0.74 | HTT (0.71) | L3MBTL1HTTRAB9APOLBKMT2A | |
| SCHEMBL595214 | 0.73 | RAB9A (0.67) | L3MBTL1HTTRAB9APOLBKMT2A | |
| SCHEMBL595212 | 0.73 | RAB9A (0.67) | L3MBTL1HTTRAB9APOLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |