Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.56 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.54 |
| ▸ | NPC1 | O15118 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.52 |
| ▸ | NAMPT | P43490 | 1/20 | 0.52 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28799461 | 0.96 | LMNA (0.58) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL25877653 | 0.93 | LMNA (0.60) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL4089988 | 0.84 | HTT (0.57) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL7823892 | 0.84 | L3MBTL1 (0.64) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL11731380 | 0.79 | NAMPT (0.52) | MEN1KMT2AMAPTRAB9ANPC1 | |
| SCHEMBL28649332 | 0.77 | NAMPT (0.85) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL2853073 | 0.77 | LMNA (0.73) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL2853072 | 0.77 | LMNA (0.73) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL6469075 | 0.77 | HCAR3 (0.46) | MEN1KMT2ALMNAMAPTHTT | |
| SCHEMBL1504563 | 0.77 | RAB9A (0.72) | MEN1KMT2ALMNAMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017049401-A1 | NEW BENZIMIDAZOLES DERIVATIVES AS TEC KINASES FAMILY INHIBITORS | PHARMASCIENCE INC. (CA) | 2017-03-30 | — | — | WO | disclosed |
| WO-2014024119-A1 | HETEROCYCLIC AMIDES AS ITK INHIBITORS | GLENMARK PHARMACEUTICALS S.A. (CH) | 2014-02-13 | — | — | WO | disclosed |
| EP-1060166-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | Boehringer Ingelheim Pharma KG (DE) | 2000-12-20 | — | — | EP | disclosed |
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |
| WO-1999040072-A1 | FIVE-MEMBERED, BENZO-CONDENSED HETEROCYCLES USED AS ANTITHROMBOTIC AGENTS | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-08-12 | — | — | WO | disclosed |