Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LSS | P48449 | 4/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.39 |
| ▸ | NOS3 | P29474 | 2/20 | 0.38 |
| ▸ | NOS1 | P29475 | 2/20 | 0.38 |
| ▸ | NOS2 | P35228 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6653536 | 0.96 | LSS (0.53) | LSSHRH3SLC6A2SLC6A4NOS3 | |
| SCHEMBL23074668 | 0.80 | LSS (0.46) | LSSTDP1 | |
| SCHEMBL12460718 | 0.79 | HRH3 (0.48) | LSSHRH3SLC6A2SLC6A4NOS3 | |
| SCHEMBL15114960 | 0.79 | GPR119 (0.46) | LSSHRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL15114937 | 0.79 | LSS (0.53) | LSS | |
| SCHEMBL15114875 | 0.77 | LSS (0.41) | LSSHRH3SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL23640419 | 0.76 | HRH3 (0.42) | LSSHRH3SLC6A2SLC6A4NOS3 | |
| SCHEMBL4325830 | 0.75 | ITGB3 (0.46) | SLC6A2SLC6A4TDP1SLC6A3 | |
| Hydrochloric Acid SCHEMBL4147694 | 0.74 | ITGB3 (0.45) | SLC6A2SLC6A4TDP1SLC6A3 | |
| SCHEMBL14050514 | 0.74 | LSS (0.49) | LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0842174-B1 | HETEROCYCLIC COMPOUNDS FOR TREATING MYOCARDIAL ISCHAEMIA | PF MEDICAMENT (FR) | 2001-10-04 | — | — | EP | disclosed |