Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 6/20 | 0.59 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.59 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9509388 | 0.96 | HDAC3 (0.53) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL7814770 | 0.87 | NR4A2 (0.55) | L3MBTL1LMNATBXAS1HPGDATM | |
| SCHEMBL5253811 | 0.86 | L3MBTL1 (0.46) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5253810 | 0.86 | L3MBTL1 (0.46) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL9110108 | 0.84 | ALDH1A1 (0.46) | HDAC8HDAC1HDAC3HDAC4HDAC7 | |
| SCHEMBL5416922 | 0.84 | HTT (0.51) | HDAC8HDAC1MAPTLMNAATM | |
| SCHEMBL28223023 | 0.84 | HTT (0.51) | HDAC8HDAC1MAPTLMNAATM | |
| SCHEMBL15844766 | 0.84 | HTT (0.51) | HDAC8HDAC1MAPTLMNAATM | |
| SCHEMBL15844695 | 0.84 | HTT (0.51) | HDAC8HDAC1MAPTLMNAATM | |
| SCHEMBL15979732 | 0.82 | ALDH1A1 (0.53) | MAPTL3MBTL1LMNAHPGDATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |