Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 6/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5253811 | 0.84 | L3MBTL1 (0.46) | ALDH1A1HPGDSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL7824225 | 0.84 | HDAC8 (0.59) | ALDH1A1HPGDSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL5253810 | 0.84 | L3MBTL1 (0.46) | ALDH1A1HPGDSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL15844695 | 0.83 | HTT (0.51) | ALDH1A1LMNAMAPTHDAC1HDAC8 | |
| SCHEMBL28223023 | 0.83 | HTT (0.51) | ALDH1A1LMNAMAPTHDAC1HDAC8 | |
| SCHEMBL15844766 | 0.83 | HTT (0.51) | ALDH1A1LMNAMAPTHDAC1HDAC8 | |
| SCHEMBL5416922 | 0.83 | HTT (0.51) | ALDH1A1LMNAMAPTHDAC1HDAC8 | |
| SCHEMBL15979732 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL30089542 | 0.81 | ALDH1A1 (0.53) | ALDH1A1HPGDSMN1; SMN2HSD17B10L3MBTL1 | |
| SCHEMBL2113189 | 0.81 | CYP19A1 (0.51) | ALDH1A1HPGDSMN1; SMN2L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1114834-A | antidiabetic agent | OTSUKA PHARMA CO LTD (JP) | 1996-01-10 | — | — | CN | disclosed |
| EP-0670831-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1995-09-13 | — | — | EP | disclosed |
| WO-1995009159-A1 | QUINOXALINE DERIVATIVE AS ANTIDIABETIC AGENT | OTSUKA PHARMACEUTICAL COMPANY, LIMITED (JP) | 1995-04-06 | — | — | WO | disclosed |