Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.36 |
| ▸ | USP36 | Q9P275 | 1/20 | 0.36 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TGM2 | P21980 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL28557709 | 0.85 | HCAR2 (0.47) | HCAR2LMNATAS2R14GLAHPGD | |
| Formic Acid SCHEMBL28229618 | 0.83 | LMNA (0.42) | HCAR2LMNAGLAHPGDALDH1A1 | |
| SCHEMBL29111925 | 0.83 | CYP19A1 (0.39) | HCAR2LMNATAS2R14ALDH1A1CYP19A1 | |
| SCHEMBL876019 | 0.82 | CYP19A1 (0.43) | HCAR2NPC1RAB9AALDH1A1CYP19A1 | |
| Propionic Acid SCHEMBL28134495 | 0.81 | AGBL2 (0.45) | HCAR2TAS2R14RAB9AGLAHPGD | |
| Hydrochloric Acid SCHEMBL27566786 | 0.80 | CYP19A1 (0.42) | HCAR2NPC1RAB9AALDH1A1CYP19A1 | |
| Acetamide SCHEMBL28112655 | 0.80 | ALDH1A1 (0.47) | HCAR2LMNARAB9AHPGDALDH1A1 | |
| Cyanide SCHEMBL27815567 | 0.77 | CYP19A1 (0.43) | HCAR2NPC1RAB9AALDH1A1CYP19A1 | |
| Alcohol SCHEMBL28895679 | 0.76 | DDR1 (0.41) | HCAR2ALDH1A1CYP19A1CYP11B2DDR1 | |
| SCHEMBL28802823 | 0.74 | DDR1 (0.41) | HCAR2LMNATAS2R14RAB9AGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |