Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 6/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.38 |
| ▸ | HTR2B | P41595 | 3/20 | 0.38 |
| ▸ | HTR2A | P28223 | 2/20 | 0.38 |
| ▸ | HTR2C | P28335 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8690809 | 0.89 | HTR2B (0.38) | MTNR1AMTNR1BHTR2BHTR2AHTR2C | |
| SCHEMBL7824590 | 0.88 | MPO (0.41) | MTNR1AMTNR1BHTR2AHTR2CALDH1A1 | |
| SCHEMBL8694687 | 0.88 | HTR2B (0.38) | MTNR1AMTNR1BHTR2BHTR2AHTR2C | |
| SCHEMBL8599471 | 0.83 | LTA4H (0.41) | KDM4EKMT2AALDH1A1MEN1MAPT | |
| SCHEMBL8690899 | 0.77 | MPO (0.31) | — | |
| SCHEMBL7817703 | 0.73 | HTR2A (0.43) | MTNR1AMTNR1BHTR2BHTR2AHTR2C | |
| SCHEMBL7824434 | 0.73 | HTR2A (0.44) | MTNR1AMTNR1BHTR2BHTR2AHTR2C | |
| SCHEMBL7817689 | 0.62 | HTR2C (0.39) | HTR2BHTR2AHTR2CKDM4ETRPV1 | |
| SCHEMBL16495066 | 0.62 | MTNR1A (0.70) | MTNR1AMTNR1BHTR2BHTR2AHTR2C | |
| SCHEMBL29003613 | 0.62 | HTR2B (0.59) | MTNR1AMTNR1BHTR2BHTR2AHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0861248-B1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PROD (US) | 2001-12-12 | — | — | EP | disclosed |
| EP-0861248-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1998-09-02 | — | — | EP | disclosed |
| WO-1997017343-A1 | INDOLEALKYL DERIVATIVES OF BENZODIOXANMETHYLAMINE AS 5-HT1A RECEPTOR LIGANDS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1997-05-15 | — | — | WO | disclosed |