Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 11/20 | 0.43 |
| ▸ | MMP2 | P08253 | 4/20 | 0.43 |
| ▸ | MMP3 | P08254 | 3/20 | 0.43 |
| ▸ | MMP13 | P45452 | 10/20 | 0.42 |
| ▸ | MMP9 | P14780 | 10/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322130 | 0.87 | MMP13 (0.47) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7453357 | 0.84 | MMP13 (0.57) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7820004 | 0.84 | TAS1R3 (0.43) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7825679 | 0.83 | MMP13 (0.44) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7318219 | 0.78 | MMP13 (0.56) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7323850 | 0.78 | PLK1 (0.46) | MMP1MMP13MMP9ADAM17ALDH1A1 | |
| SCHEMBL7315984 | 0.76 | MMP13 (0.42) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL7322284 | 0.75 | MMP13 (0.52) | MMP1MMP2MMP3MMP13MMP9 | |
| SCHEMBL6815791 | 0.74 | MMP13 (0.60) | MMP1MMP2MMP13MMP9ADAM17 | |
| SCHEMBL7576696 | 0.74 | BCHE (0.43) | MMP1MMP2MMP3MMP13MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938471-B1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID CO (US) | 2001-12-12 | — | — | EP | claimed |