Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 5/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 5/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 3/20 | 0.42 |
| ▸ | MMP13 | P45452 | 3/20 | 0.42 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.42 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP3 | P08254 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
| ▸ | PTAFR | P25105 | 5/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | MMP12 | P39900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7825682 | 0.84 | MMP1 (0.43) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL7820002 | 0.83 | PTGS2 (0.41) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL7316088 | 0.79 | MMP13 (0.45) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL7820104 | 0.79 | MMP13 (0.45) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL7322130 | 0.79 | MMP13 (0.47) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL7820407 | 0.77 | PTAFR (0.40) | TAS1R3TAS1R1GAARECQLMMP9 | |
| SCHEMBL7830182 | 0.76 | TRPM8 (0.48) | MMP9MMP13ADAM17MMP1MMP12 | |
| SCHEMBL7318219 | 0.76 | MMP13 (0.56) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL7315984 | 0.75 | MMP13 (0.42) | MMP9MMP13ADAM17MMP1MMP2 | |
| SCHEMBL7572045 | 0.75 | PTGS2 (0.41) | MMP9MMP13ADAM17MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938471-B1 | THE PREPARATION AND USE OF ORTHO-SULFONAMIDO ARYL HYDROXAMIC ACIDS AS MATRIX METALLOPROTEINASE AND TACE INHIBITORS | AMERICAN CYANAMID CO (US) | 2001-12-12 | — | — | EP | claimed |