Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.61 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.58 |
| ▸ | NPC1 | O15118 | 7/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.55 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.55 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.54 |
| ▸ | TP53 | P04637 | 3/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12189568 | 0.86 | FAAH (0.56) | TP53GAAHTT | |
| SCHEMBL12835024 | 0.86 | FAAH (0.56) | TP53GAAHTT | |
| SCHEMBL12189542 | 0.86 | FAAH (0.56) | TP53GAAHTT | |
| SCHEMBL12189553 | 0.84 | NPC1 (0.57) | TAS1R3TAS1R1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL12172966 | 0.81 | LMNA (0.58) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL12189601 | 0.80 | PGR (0.60) | SMN1; SMN2LMNAMAPTKMT2AMEN1 | |
| SCHEMBL12172975 | 0.79 | RAB9A (0.53) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL7824986 | 0.79 | CYP1A2 (0.55) | SMN1; SMN2NPC1RAB9ALMNAMAPT | |
| SCHEMBL16168014 | 0.78 | HSD17B10 (0.42) | TAS1R3TAS1R1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL11252690 | 0.78 | EPHX2 (0.56) | SMN1; SMN2NPC1RAB9AMAPTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091958-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2001-04-18 | — | — | EP | disclosed |
| WO-2000001692-A1 | SALTS OF PAROXETINE | SMITHKLINE BEECHAM PLC (GB) | 2000-01-13 | — | — | WO | disclosed |